Endocrine and Organ Specific Autoimmunity George S. Eisenbarth

ISBN: 9781570595387

Published: June 15th 1999

Hardcover

271 pages


Description

Endocrine and Organ Specific Autoimmunity  by  George S. Eisenbarth

Endocrine and Organ Specific Autoimmunity by George S. Eisenbarth
June 15th 1999 | Hardcover | PDF, EPUB, FB2, DjVu, talking book, mp3, RTF | 271 pages | ISBN: 9781570595387 | 7.73 Mb

Organ specific autoimmune disorders as a group are responsible for a major portion of all debilitating and at times life threatening chronic diseases. Over the past decade more has been learned concerning the molecular pathogenesis of these disordersMoreOrgan specific autoimmune disorders as a group are responsible for a major portion of all debilitating and at times life threatening chronic diseases. Over the past decade more has been learned concerning the molecular pathogenesis of these disorders than during the past 100 years.

This includes identification of genes and genetic loci responsible for susceptibility, specific molecules whose ingestion or whose endogenous exposure (e.g. oncogenic autoimmunity) trigger disease, cloning of target autoantigens, identification of molecular pathways of pathogenesis, and discovery particularly in animal models of antigen specific therapies. The current book brings together under an integrated theme, international experts who have contributed to the study of both specific autoimmune disorders and often the study of multiple organ specific autoimmune diseases.

Both basic researchers and clinical investigators have contributed to the book and the current and future impa! ct upon clinical care of our improving understanding of disease pathogenesis is highlighted. The present includes the diagnosis and prediction of organ specific autoimmune diseases with assay based upon cloned target autoantigens. The future will hopefully test our ability to prevent or ameliorate disease with these same molecules. In the study of the multiple diseases reviewed it is hoped that many of the roads will lead to the same destination, namely molecular disease prevention and it is hoped that the current book will help in reaching this goal.



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